Steatotic Liver Disease: Metabolic Dysfunction, Alcohol, or Both?

Non-alcoholic fatty liver disease (NAFLD) and alcohol-related (ALD), both of them accounting for (FLD), are among the most common chronic diseases globally, contributing to substantial public health burden. Both NAFLD ALD share a similar picture clinical presentation yet may have differences in prognosis treatment, which renders early accurate diagnosis difficult but necessary. While is fastest increasing disease, prevalence has seemingly remained stable recent years. Lately, term steatotic (SLD) been introduced, replacing FLD reduce stigma. SLD represents an overarching primarily comprise metabolic dysfunction-associated (MASLD), formerly known as non-alcoholic (NAFLD), well MetALD, defined continuum across contribution MASLD varies. The present review discusses current knowledge on denominators NAFLD/MASLD order highlight research needs improve our understanding SLD.